AmiodaroneĪmiodarone should be avoided in the treatment of patients with WPW related atrial fibrillation. Regardless of the administration strategy, procainamide has a relatively slow onset of action and may not reach therapeutic blood levels for 40 to 60 minutes. Patients who are treated with procainamide should be placed on continuous cardiac monitor and have frequent assessments of blood pressure. the QRS complex widens by 50% or more from its original width.Procainamide is dosed at 20 to 30 mg/minute, until the dysrhythmia is terminated or one of the following end points is reached: Procainamide is the primary agent for control of WPW-related atrial fibrillation in the stable patient. Read More about Management of Atrial Fibrillation (AF) with Rapid Ventricular Response (RVR) Procainamide Cardiology consultation should also be obtained. Once the patient is stabilized and the rhythm converted to sinus rhythm, admission to a monitored critical care bed is most appropriate.
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